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Study Identifies Cause of Severe Pain in SM-affected Cavaliers

Professor Clare RusbridgeProfessor Clare Rusbridge has shared a positive and encouraging update from research made possible by the Cavalier Tissue Collection Scheme. For those whose Cavaliers were part of this project, it is heartening to know that their legacy is already helping to deepen understanding of syringomyelia and may lead to better outcomes for future dogs.

A recent study, carried out by researchers at the University of Copenhagen, explored why some Cavaliers with syringomyelia (SM) develop severe, difficult-to-control neuropathic pain. Using advanced techniques to study spinal cord tissue, the research identified changes in key support and immune cells that appear to drive inflammation and chronic pain.

These findings mark an important step forward in understanding the biological processes behind syringomyelia-related pain and could help guide improved treatments and pain management in the future.

This research would not have been possible without the quiet generosity of owners who chose to donate their beloved dogs to science, along with the dedication of vets, researchers and fundraisers. We extend our heartfelt thanks to everyone involved in the Cavalier Tissue Collection Scheme, including Margaret Carter and Cavalier Matters whose work continues to make a lasting difference.

Above all, thank you to Clare Rusbridge for her tireless dedication to Cavalier health. Through research, collaboration and compassion, she and her colleagues are helping to shape a healthier future for this much-loved breed.

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